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Analysis of gene expression and mutation data points on contribution of transcription to the mutagenesis by APOBEC enzymes
Since the discovery of the role of the APOBEC enzymes in human cancers, the mechanisms of this type of mutagenesis remain little understood. Theoretically, targeting of single-stranded DNA by the APOBEC enzymes could occur during cellular processes leading to the unwinding of DNA double-stranded str...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253550/ https://www.ncbi.nlm.nih.gov/pubmed/34316712 http://dx.doi.org/10.1093/narcan/zcab025 |