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Cancer-associated fibroblast-induced M2-polarized macrophages promote hepatocellular carcinoma progression via the plasminogen activator inhibitor-1 pathway

Targeting the tumor stroma is an important strategy in cancer treatment. Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs) are two main components in the tumor microenvironment (TME) in hepatocellular carcinoma (HCC), which can promote tumor progression. Plasminogen activa...

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Detalles Bibliográficos
Autores principales: Chen, Shuhai, Morine, Yuji, Tokuda, Kazunori, Yamada, Shinichiro, Saito, Yu, Nishi, Masaaki, Ikemoto, Tetsuya, Shimada, Mitsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253588/
https://www.ncbi.nlm.nih.gov/pubmed/34195849
http://dx.doi.org/10.3892/ijo.2021.5239