The molecular basis of coupling between poly(A)-tail length and translational efficiency

In animal oocytes and early embryos, mRNA poly(A)-tail length strongly influences translational efficiency (TE), but later in development this coupling between tail length and TE disappears. Here, we elucidate how this coupling is first established and why it disappears. Overexpressing cytoplasmic p...

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Detalles Bibliográficos
Autores principales: Xiang, Kehui, Bartel, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://www.ncbi.nlm.nih.gov/pubmed/34213414
http://dx.doi.org/10.7554/eLife.66493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253595/
https://www.ncbi.nlm.nih.gov/pubmed/34213414
http://dx.doi.org/10.7554/eLife.66493

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