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Multiscale modeling of genome organization with maximum entropy optimization

Three-dimensional (3D) organization of the human genome plays an essential role in all DNA-templated processes, including gene transcription, gene regulation, and DNA replication. Computational modeling can be an effective way of building high-resolution genome structures and improving our understan...

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Detalles Bibliográficos
Autores principales: Lin, Xingcheng, Qi, Yifeng, Latham, Andrew P., Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253599/
https://www.ncbi.nlm.nih.gov/pubmed/34241389
http://dx.doi.org/10.1063/5.0044150