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Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver

Sexual dimorphism in gene regulation, including DNA methylation, is the main driver of sexual dimorphism in phenotypes. However, the questions of how and when sex shapes DNA methylation remain unresolved. Recently, using mice with different combinations of genetic and phenotypic sex, we identified s...

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Detalles Bibliográficos
Autores principales: AlOgayil, Najla, Bauermeister, Klara, Galvez, Jose Hector, Venkatesh, Varun S., Zhuang, Qinwei Kim-wee, Chang, Matthew L., Davey, Rachel A., Zajac, Jeffrey D., Ida, Kinuyo, Kamiya, Akihide, Taketo, Teruko, Bourque, Guillaume, Naumova, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253761/
https://www.ncbi.nlm.nih.gov/pubmed/34215813
http://dx.doi.org/10.1038/s41598-021-93216-6