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Growth differentiation factor 11 attenuates cardiac ischemia reperfusion injury via enhancing mitochondrial biogenesis and telomerase activity

It has been reported that growth differentiation factor 11 (GDF11) protects against myocardial ischemia/reperfusion (IR) injury, but the underlying mechanisms have not been fully clarified. Considering that GDF11 plays a role in the aging/rejuvenation process and that aging is associated with telome...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Luo, Guangjin, Liu, Yameng, Lin, Hairuo, Zheng, Cankun, Xie, Dongxiao, Zhu, Yingqi, Chen, Lu, Huang, Xiaoxia, Hu, Donghong, Xie, Jiahe, Chen, Zhenhuan, Liao, Wangjun, Bin, Jianping, Wang, Qiancheng, Liao, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253774/
https://www.ncbi.nlm.nih.gov/pubmed/34215721
http://dx.doi.org/10.1038/s41419-021-03954-8