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Downregulated lncRNA RCPCD promotes differentiation of embryonic stem cells into cardiac pacemaker-like cells by suppressing HCN4 promoter methylation

Long non-coding RNA (lncRNA) is receiving increasing attention in embryonic stem cells (ESCs) research. However, the roles of lncRNA in the differentiation of ESCs into pacemaker-like cells are still unclear. Therefore, the present study aims to explore the roles and mechanisms of lncRNA in the diff...

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Detalles Bibliográficos
Autores principales: Zhu, Ye, You, Jia, Wei, Wei, Gu, Jianjun, Xu, Chao, Gu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253811/
https://www.ncbi.nlm.nih.gov/pubmed/34215719
http://dx.doi.org/10.1038/s41419-021-03949-5