Revealing the Dynamic Allosteric Changes Required for Formation of the Cysteine Synthase Complex by Hydrogen-Deuterium Exchange MS

CysE and CysK, the last two enzymes of the cysteine biosynthetic pathway, engage in a bienzyme complex, cysteine synthase, with yet incompletely characterized three-dimensional structure and regulatory function. Being absent in mammals, the two enzymes and their complex are attractive targets for an...

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Detalles Bibliográficos
Autores principales: Rosa, Brenda, Dickinson, Eleanor R., Marchetti, Marialaura, Campanini, Barbara, Pioselli, Barbara, Bettati, Stefano, Rand, Kasper Dyrberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253905/
https://www.ncbi.nlm.nih.gov/pubmed/34022432
http://dx.doi.org/10.1016/j.mcpro.2021.100098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253905/
https://www.ncbi.nlm.nih.gov/pubmed/34022432
http://dx.doi.org/10.1016/j.mcpro.2021.100098

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