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Glucose treatment of human pancreatic β-cells enhances translation of mRNAs involved in energetics and insulin secretion

Glucose-mediated signaling regulates the expression of a limited number of genes in human pancreatic β-cells at the transcriptional level. However, it is unclear whether glucose plays a role in posttranscriptional RNA processing or translational control of gene expression. Here, we asked whether glu...

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Detalles Bibliográficos
Autores principales: Zakaria, Albatoul, Berthault, Claire, Cosson, Bertrand, Jung, Vincent, Guerrera, Ida Chiara, Rachdi, Latif, Scharfmann, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253965/
https://www.ncbi.nlm.nih.gov/pubmed/34051232
http://dx.doi.org/10.1016/j.jbc.2021.100839