Protein-aggregating ability of different protoporphyrin-IX nanostructures is dependent on their oxidation and protein-binding capacity

Porphyrias are rare blood disorders caused by genetic defects in the heme biosynthetic pathway and are associated with the accumulation of high levels of porphyrins that become cytotoxic. Porphyrins, due to their amphipathic nature, spontaneously associate into different nanostructures, but very lit...

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Detalles Bibliográficos
Autores principales: Maitra, Dhiman, Pinsky, Benjamin M., Soherawardy, Amenah, Zheng, Haiyan, Banerjee, Ruma, Omary, M. Bishr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253973/
https://www.ncbi.nlm.nih.gov/pubmed/34023387
http://dx.doi.org/10.1016/j.jbc.2021.100778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253973/
https://www.ncbi.nlm.nih.gov/pubmed/34023387
http://dx.doi.org/10.1016/j.jbc.2021.100778

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