Cargando…

Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin

Camptothecin is a clinically important monoterpene indole alkaloid (MIAs) used for treating various cancers. Currently, the production of this biopharmaceutical hinges on its extraction from camptothecin-producing plants, leading to high market prices and supply bottlenecks. While synthetic biology...

Descripción completa

Detalles Bibliográficos
Autores principales: Stander, Emily Amor, Dugé de Bernonville, Thomas, Papon, Nicolas, Courdavault, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254074/
https://www.ncbi.nlm.nih.gov/pubmed/34257844
http://dx.doi.org/10.1016/j.csbj.2021.06.028