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Computational biotechnology guides elucidation of the biosynthesis of the plant anticancer drug camptothecin
Camptothecin is a clinically important monoterpene indole alkaloid (MIAs) used for treating various cancers. Currently, the production of this biopharmaceutical hinges on its extraction from camptothecin-producing plants, leading to high market prices and supply bottlenecks. While synthetic biology...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254074/ https://www.ncbi.nlm.nih.gov/pubmed/34257844 http://dx.doi.org/10.1016/j.csbj.2021.06.028 |