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Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans

Understanding the molecular mechanisms governing antifungal resistance is crucial for identifying new cellular targets for developing new antifungal therapeutics. In this study, we performed a transposon-mediated genome-wide genetic screen in haploid Candida albicans to identify mutants resistant to...

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Detalles Bibliográficos
Autores principales: Zeng, Guisheng, Xu, Xiaoli, Gao, Jiaxin, da Silva Dantas, Alessandra, Gow, Neil A.R., Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254124/
https://www.ncbi.nlm.nih.gov/pubmed/34258484
http://dx.doi.org/10.1016/j.tcsw.2021.100057