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Inactivating the mannose-ethanolamine phosphotransferase Gpi7 confers caspofungin resistance in the human fungal pathogen Candida albicans
Understanding the molecular mechanisms governing antifungal resistance is crucial for identifying new cellular targets for developing new antifungal therapeutics. In this study, we performed a transposon-mediated genome-wide genetic screen in haploid Candida albicans to identify mutants resistant to...
Autores principales: | Zeng, Guisheng, Xu, Xiaoli, Gao, Jiaxin, da Silva Dantas, Alessandra, Gow, Neil A.R., Wang, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254124/ https://www.ncbi.nlm.nih.gov/pubmed/34258484 http://dx.doi.org/10.1016/j.tcsw.2021.100057 |
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