Isolation and characterization of fetal nucleated red blood cells from maternal blood as a target for single cell sequencing‐based non‐invasive genetic testing

PURPOSE: Although non‐invasive prenatal testing (NIPT) based on cell‐free DNA (cfDNA) in maternal plasma has been prevailing worldwide, low levels of fetal DNA fraction may lead to false‐negative results. Since fetal cells in maternal blood provide a pure source of fetal genomic DNA, we aimed to est...

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Detalles Bibliográficos
Autores principales: Ito, Noriko, Tsukamoto, Kazuhiro, Taniguchi, Kosuke, Takahashi, Ken, Okamoto, Aikou, Aoki, Hiroaki, Otera‐Takahashi, Yuka, Kitagawa, Michihiro, Ogata‐Kawata, Hiroko, Morita, Hideaki, Hata, Kenichiro, Nakabayashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254165/
https://www.ncbi.nlm.nih.gov/pubmed/34262404
http://dx.doi.org/10.1002/rmb2.12392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254165/
https://www.ncbi.nlm.nih.gov/pubmed/34262404
http://dx.doi.org/10.1002/rmb2.12392

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