Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1‐phosphate in extravillous trophoblasts

PURPOSE: Extracellular matrix remodeling is essential for extravillous trophoblast (EVT) cell migration and invasion during placental development and regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs). Sphingosine kinases (SPHK1 and SPHK2) synthesize sphi...

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Detalles Bibliográficos
Autores principales: Chahar, Kirti R., Kumar, Vijay, Sharma, Phulwanti K., Brünnert, Daniela, Kaushik, Vibha, Gehlot, Pragya, Shekhawat, Indu, Kumar, Suman, Sharma, Ajay Kumar, Kumari, Sandhya, Goyal, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254167/
https://www.ncbi.nlm.nih.gov/pubmed/34262394
http://dx.doi.org/10.1002/rmb2.12379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254167/
https://www.ncbi.nlm.nih.gov/pubmed/34262394
http://dx.doi.org/10.1002/rmb2.12379

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