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Sphingosine kinases negatively regulate the expression of matrix metalloproteases (MMP1 and MMP3) and their inhibitor TIMP3 genes via sphingosine 1‐phosphate in extravillous trophoblasts
PURPOSE: Extracellular matrix remodeling is essential for extravillous trophoblast (EVT) cell migration and invasion during placental development and regulated by matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteases (TIMPs). Sphingosine kinases (SPHK1 and SPHK2) synthesize sphi...
Autores principales: | Chahar, Kirti R., Kumar, Vijay, Sharma, Phulwanti K., Brünnert, Daniela, Kaushik, Vibha, Gehlot, Pragya, Shekhawat, Indu, Kumar, Suman, Sharma, Ajay Kumar, Kumari, Sandhya, Goyal, Pankaj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254167/ https://www.ncbi.nlm.nih.gov/pubmed/34262394 http://dx.doi.org/10.1002/rmb2.12379 |
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