Optimizing interleukin-2 concentration, seeding density and bead-to-cell ratio of T-cell expansion for adoptive immunotherapy

BACKGROUND: The successful ex vivo expansion of T-cells in great numbers is the cornerstone of adoptive cell therapy. We aimed to achieve the most optimal T-cell expansion condition by comparing the expansion of T-cells at various seeding densities, IL-2 concentrations, and bead-to-cell ratios. we f...

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Detalles Bibliográficos
Autores principales: Ghaffari, Sasan, Torabi-Rahvar, Monireh, Aghayan, Sajjad, Jabbarpour, Zahra, Moradzadeh, Kobra, Omidkhoda, Azadeh, Ahmadbeigi, Naser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254233/
https://www.ncbi.nlm.nih.gov/pubmed/34217218
http://dx.doi.org/10.1186/s12865-021-00435-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254233/
https://www.ncbi.nlm.nih.gov/pubmed/34217218
http://dx.doi.org/10.1186/s12865-021-00435-7

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