MSCs‑derived exosomes attenuate ischemia-reperfusion brain injury and inhibit microglia apoptosis might via exosomal miR-26a-5p mediated suppression of CDK6

BACKGROUND: This study aimed to explore the role of mesenchymal stromal cells (MSCs)-derived exosomes (MSCs-Exo) in the cerebral ischemia–reperfusion (I/R) injury. METHODS: Exosomes were isolated from MSCs of adult C57BL/6J mice by the gradient centrifugation method. The expression of miR-26a-5p and...

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Detalles Bibliográficos
Autores principales: Cheng, Chang, Chen, Xiuying, Wang, Yuhan, Cheng, Wenchao, Zuo, Xuzheng, Tang, Weiju, Huang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254277/
https://www.ncbi.nlm.nih.gov/pubmed/34215174
http://dx.doi.org/10.1186/s10020-021-00324-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254277/
https://www.ncbi.nlm.nih.gov/pubmed/34215174
http://dx.doi.org/10.1186/s10020-021-00324-0

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