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Protectin conjugates in tissue regeneration 1 restores lipopolysaccharide-induced pulmonary endothelial glycocalyx loss via ALX/SIRT1/NF-kappa B axis

BACKGROUND: Endothelial glycocalyx loss is integral to increased pulmonary vascular permeability in sepsis-related acute lung injury. Protectin conjugates in tissue regeneration 1 (PCTR1) is a novel macrophage-derived lipid mediator exhibiting potential anti-inflammatory and pro-resolving benefits....

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Detalles Bibliográficos
Autores principales: Wang, Xin-Yang, Li, Xin-Yu, Wu, Cheng-Hua, Hao, Yu, Fu, Pan-Han, Mei, Hong-Xia, Chen, Fang, Gong, Yu-Qiang, Jin, Sheng-Wei, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254367/
https://www.ncbi.nlm.nih.gov/pubmed/34217286
http://dx.doi.org/10.1186/s12931-021-01793-x