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Protectin conjugates in tissue regeneration 1 restores lipopolysaccharide-induced pulmonary endothelial glycocalyx loss via ALX/SIRT1/NF-kappa B axis

BACKGROUND: Endothelial glycocalyx loss is integral to increased pulmonary vascular permeability in sepsis-related acute lung injury. Protectin conjugates in tissue regeneration 1 (PCTR1) is a novel macrophage-derived lipid mediator exhibiting potential anti-inflammatory and pro-resolving benefits....

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Detalles Bibliográficos
Autores principales:	Wang, Xin-Yang, Li, Xin-Yu, Wu, Cheng-Hua, Hao, Yu, Fu, Pan-Han, Mei, Hong-Xia, Chen, Fang, Gong, Yu-Qiang, Jin, Sheng-Wei, Li, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254367/ https://www.ncbi.nlm.nih.gov/pubmed/34217286 http://dx.doi.org/10.1186/s12931-021-01793-x

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