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Control of coronavirus infection through plasmacytoid dendritic-cell–derived type I interferon

This study demonstrates a unique and crucial role of plasmacytoid dendritic cells (pDCs) and pDC-derived type I interferons (IFNs) in the pathogenesis of mouse coronavirus infection. pDCs controlled the fast replicating mouse hepatitis virus (MHV) through the immediate production of type I IFNs. Rec...

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Detalles Bibliográficos
Autores principales: Cervantes-Barragan, Luisa, Züst, Roland, Weber, Friedemann, Spiegel, Martin, Lang, Karl S., Akira, Shizuo, Thiel, Volker, Ludewig, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254533/
https://www.ncbi.nlm.nih.gov/pubmed/16985170
http://dx.doi.org/10.1182/blood-2006-05-023770