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Bioinformatics Analysis of Choriocarcinoma-Related MicroRNA-Transcription Factor-Target Gene Regulatory Networks and Validation of Key miRNAs

OBJECTIVE: The aim of the current research was to construct a miRNA-transcription factor (TF)-target gene regulatory network in order to investigate the mechanism underlying choriocarcinoma and to verify the network through the overexpression or silencing of hub miRNAs in vitro. MATERIALS AND METHOD...

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Detalles Bibliográficos
Autores principales: Peng, Xiaotong, Zhang, Zhirong, Mo, Yanqun, Liu, Junliang, Wang, Shuo, Liu, Huining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254590/
https://www.ncbi.nlm.nih.gov/pubmed/34234459
http://dx.doi.org/10.2147/OTT.S311291