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SARS-CoV-2 Spike protein enhances ACE2 expression via facilitating Interferon effects in bronchial epithelium

OBJECTIVE: In this study, we focused on the interaction between SARS-CoV-2 and host Type I Interferon (IFN) response, so as to identify whether IFN effects could be influenced by the products of SARS-CoV-2. METHODS: All the structural and non-structural proteins of SARS-CoV-2 were transfected and ov...

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Detalles Bibliográficos
Autores principales: Zhou, Ye, Wang, Mu, Li, Yunhui, Wang, Peihui, Zhao, Ping, Yang, Zixuan, Wang, Suyuan, Zhang, Liyuan, Li, Zhenyang, Jia, Kaiwei, Zhong, Cuiping, Li, Nan, Yu, Yizhi, Hou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Federation of Immunological Societies. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254647/
https://www.ncbi.nlm.nih.gov/pubmed/34228987
http://dx.doi.org/10.1016/j.imlet.2021.06.008