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Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells

Prion disease is a neurodegenerative disorder with progressive neurologic symptoms and accelerated cognitive decline. The causative protein of prion disease is the prion protein (PrP), and structural transition of PrP from the normal helix rich form (PrP(C)) to the abnormal β-sheet rich form (PrP(Sc...

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Detalles Bibliográficos
Autores principales: Shimizu, Takuto, Nogami, Emiko, Ito, Yuka, Morikawa, Kazuo, Nagane, Masaki, Yamashita, Tadashi, Ogawa, Tsuyoshi, Kametani, Fuyuki, Yagi, Hisashi, Hachiya, Naomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254714/
https://www.ncbi.nlm.nih.gov/pubmed/34043140
http://dx.doi.org/10.1007/s11064-021-03344-8