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Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity

The maintenance of lysosomal integrity is essential for lysosome function and cell fate. Damaged lysosomes are degraded by lysosomal autophagy, lysophagy. The mechanism underlying lysophagy remains largely unknown; this study aimed to contribute to the understanding of this topic. A cell-based scree...

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Detalles Bibliográficos
Autores principales: Park, Na Yeon, Jo, Doo Sin, Kim, Yong Hwan, Bae, Ji-Eun, Kim, Joon Bum, Park, Hyun Jun, Choi, Ji Yeon, Lee, Ha Jung, Chang, Jeong Ho, Bunch, Heeyoun, Jeon, Hong Bae, Jung, Yong-Keun, Cho, Dong-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pharmaceutical Society of Korea 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254722/
https://www.ncbi.nlm.nih.gov/pubmed/34100261
http://dx.doi.org/10.1007/s12272-021-01335-5