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Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity
The maintenance of lysosomal integrity is essential for lysosome function and cell fate. Damaged lysosomes are degraded by lysosomal autophagy, lysophagy. The mechanism underlying lysophagy remains largely unknown; this study aimed to contribute to the understanding of this topic. A cell-based scree...
Autores principales: | Park, Na Yeon, Jo, Doo Sin, Kim, Yong Hwan, Bae, Ji-Eun, Kim, Joon Bum, Park, Hyun Jun, Choi, Ji Yeon, Lee, Ha Jung, Chang, Jeong Ho, Bunch, Heeyoun, Jeon, Hong Bae, Jung, Yong-Keun, Cho, Dong-Hyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pharmaceutical Society of Korea
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254722/ https://www.ncbi.nlm.nih.gov/pubmed/34100261 http://dx.doi.org/10.1007/s12272-021-01335-5 |
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