Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation

Common genetic risk for neuropsychiatric disorders is enriched in regulatory elements active during cortical neurogenesis. However, it remains poorly understood how these variants influence gene regulation. To model the functional impact of common genetic variation on the non-coding genome during hu...

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Detalles Bibliográficos
Autores principales: Liang, Dan, Elwell, Angela L., Aygün, Nil, Krupa, Oleh, Wolter, Justin M., Kyere, Felix A., Lafferty, Michael J., Cheek, Kerry E., Courtney, Kenan P., Yusupova, Marianna, Garrett, Melanie E., Ashley-Koch, Allison, Crawford, Gregory E., Love, Michael I., de la Torre-Ubieta, Luis, Geschwind, Daniel H., Stein, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254789/
https://www.ncbi.nlm.nih.gov/pubmed/34017130
http://dx.doi.org/10.1038/s41593-021-00858-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254789/
https://www.ncbi.nlm.nih.gov/pubmed/34017130
http://dx.doi.org/10.1038/s41593-021-00858-w

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