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Hunger or thirst state-uncertainty is resolved by outcome evaluation in medial prefrontal cortex to guide decision-making

Physiological need states direct decision-making towards re-establishing homeostasis. Using a two-alternative-forced-choice task for mice that models elements of human decisions, we found that varying hunger and thirst states caused need-inappropriate choices, such as food-seeking when thirsty. Thes...

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Detalles Bibliográficos
Autores principales: Eiselt, Anne-Kathrin, Chen, Susu, Chen, Jim, Arnold, Jon, Kim, Tahnbee, Pachitariu, Marius, Sternson, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254795/
https://www.ncbi.nlm.nih.gov/pubmed/33972802
http://dx.doi.org/10.1038/s41593-021-00850-4