Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome

Homer1 is a synaptic scaffold protein that regulates glutamatergic synapses and spine morphogenesis. HOMER1 knockout (KO) mice show behavioral abnormalities related to psychiatric disorders, and HOMER1 has been associated with psychiatric disorders such as addiction, autism disorder (ASD), schizophr...

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Detalles Bibliográficos
Autores principales: Yoon, Sehyoun, Piguel, Nicolas H., Khalatyan, Natalia, Dionisio, Leonardo E., Savas, Jeffrey N., Penzes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254828/
https://www.ncbi.nlm.nih.gov/pubmed/33398084
http://dx.doi.org/10.1038/s41380-020-00991-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254828/
https://www.ncbi.nlm.nih.gov/pubmed/33398084
http://dx.doi.org/10.1038/s41380-020-00991-1

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