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Homer1 promotes dendritic spine growth through ankyrin-G and its loss reshapes the synaptic proteome
Homer1 is a synaptic scaffold protein that regulates glutamatergic synapses and spine morphogenesis. HOMER1 knockout (KO) mice show behavioral abnormalities related to psychiatric disorders, and HOMER1 has been associated with psychiatric disorders such as addiction, autism disorder (ASD), schizophr...
Autores principales: | Yoon, Sehyoun, Piguel, Nicolas H., Khalatyan, Natalia, Dionisio, Leonardo E., Savas, Jeffrey N., Penzes, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254828/ https://www.ncbi.nlm.nih.gov/pubmed/33398084 http://dx.doi.org/10.1038/s41380-020-00991-1 |
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