Whole exome sequencing and system biology analysis support the "two-hit" mechanism in the onset of Ameloblastoma

BACKGROUND: Ameloblastoma is the most frequent odontogenic tumor. Various evidence has highlighted the role of somatic mutations, including recurrent mutation BRAF V600E, in the tumorigenesis of Ameloblastoma, but the intact genetic pathology remains unknown. MATERIAL AND METHODS: We sequenced the w...

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Detalles Bibliográficos
Autores principales: Shi, Yueqi, Li, Mengyu, Yu, Yejia, Zhou, Yuqiong, Wang, Shaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254878/
https://www.ncbi.nlm.nih.gov/pubmed/33395399
http://dx.doi.org/10.4317/medoral.24385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254878/
https://www.ncbi.nlm.nih.gov/pubmed/33395399
http://dx.doi.org/10.4317/medoral.24385

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