Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons

Spinal muscular atrophy (SMA) is a neuromuscular genetic disease caused by reduced survival motor neuron (SMN) protein. SMN is ubiquitous and deficient levels cause spinal cord motoneurons (MNs) degeneration and muscle atrophy. Nevertheless, the mechanism by which SMN reduction in muscle contributes...

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Detalles Bibliográficos
Autores principales: Sansa, Alba, Hidalgo, Ivan, Miralles, Maria P., de la Fuente, Sandra, Perez-Garcia, M. Jose, Munell, Francina, Soler, Rosa M., Garcera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254901/
https://www.ncbi.nlm.nih.gov/pubmed/34217376
http://dx.doi.org/10.1186/s40478-021-01223-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254901/
https://www.ncbi.nlm.nih.gov/pubmed/34217376
http://dx.doi.org/10.1186/s40478-021-01223-5

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