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Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer’s disease in Caribbean Hispanics

BACKGROUND: Genetic studies have primarily been conducted in European ancestry populations, identifying dozens of loci associated with late-onset Alzheimer’s disease (AD). However, much of AD’s heritability remains unexplained; as the prevalence of AD varies across populations, the genetic architect...

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Detalles Bibliográficos
Autores principales: Horimoto, Andréa R. V. R., Xue, Diane, Thornton, Timothy A., Blue, Elizabeth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8254995/
https://www.ncbi.nlm.nih.gov/pubmed/34217363
http://dx.doi.org/10.1186/s13195-021-00866-9