Inhibition of EZH2 prevents acute respiratory distress syndrome (ARDS)-associated pulmonary fibrosis by regulating the macrophage polarization phenotype

BACKGROUND: We recently reported histone methyltransferase enhancer of zeste homolog 2 (EZH2) as a key epigenetic regulator that contributes to the dysfunction of innate immune responses to sepsis and subsequent lung injury by mediating the imbalance of macrophage polarization. However, the role of...

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Detalles Bibliográficos
Autores principales: Bao, Xiaowei, Liu, Xiandong, Liu, Na, Zhuang, Shougang, Yang, Qian, Ren, Huijuan, Zhao, Dongyang, Bai, Jianwen, Zhou, Xiaohui, Tang, Lunxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255011/
https://www.ncbi.nlm.nih.gov/pubmed/34217280
http://dx.doi.org/10.1186/s12931-021-01785-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255011/
https://www.ncbi.nlm.nih.gov/pubmed/34217280
http://dx.doi.org/10.1186/s12931-021-01785-x

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