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Inhibition of EZH2 prevents acute respiratory distress syndrome (ARDS)-associated pulmonary fibrosis by regulating the macrophage polarization phenotype

BACKGROUND: We recently reported histone methyltransferase enhancer of zeste homolog 2 (EZH2) as a key epigenetic regulator that contributes to the dysfunction of innate immune responses to sepsis and subsequent lung injury by mediating the imbalance of macrophage polarization. However, the role of...

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Detalles Bibliográficos
Autores principales:	Bao, Xiaowei, Liu, Xiandong, Liu, Na, Zhuang, Shougang, Yang, Qian, Ren, Huijuan, Zhao, Dongyang, Bai, Jianwen, Zhou, Xiaohui, Tang, Lunxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255011/ https://www.ncbi.nlm.nih.gov/pubmed/34217280 http://dx.doi.org/10.1186/s12931-021-01785-x

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