Novel piperazine based compounds as potential inhibitors for SARS-CoV-2 Protease Enzyme: Synthesis and molecular docking study

Structurally diverse piperazine-based compounds hybrid with thiadiazole, isatin or with sulfur/nitrogen, functionalities were synthesized. The structures of the new compounds were established based on their spectral data and elemental analysis. The physicochemical, bioactivity scores and pharmacokin...

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Detalles Bibliográficos
Autores principales: Omar, Alaa Z., Mosa, Tawfik M., El-sadany, Samer K., Hamed, Ezzat A., El-atawy, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255031/
https://www.ncbi.nlm.nih.gov/pubmed/34248201
http://dx.doi.org/10.1016/j.molstruc.2021.131020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255031/
https://www.ncbi.nlm.nih.gov/pubmed/34248201
http://dx.doi.org/10.1016/j.molstruc.2021.131020

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