Rebalancing TGF‐β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis

BACKGROUND: Liver fibrosis and fibrosis‐related hepatocarcinogenesis are a rising cause for morbidity and death worldwide. Although transforming growth factor‐β (TGF‐β) is a critical mediator of chronic liver fibrosis, targeting TGF‐β isoforms and receptors lead to unacceptable side effect. This stu...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Sun, Mayu, Li, Weida, Liu, Chaobao, Jiang, Zheshun, Gu, Pengfei, Li, Jingquan, Wang, Wei, You, Rongli, Ba, Qian, Li, Xiaoguang, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255064/
https://www.ncbi.nlm.nih.gov/pubmed/34323416
http://dx.doi.org/10.1002/ctm2.410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255064/
https://www.ncbi.nlm.nih.gov/pubmed/34323416
http://dx.doi.org/10.1002/ctm2.410

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