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CB(1)R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome

Hermansky–Pudlak syndrome (HPS) is a rare genetic disorder which, in its most common and severe form, HPS‐1, leads to fatal adult‐onset pulmonary fibrosis (PF) with no effective treatment. We evaluated the role of the endocannabinoid/CB(1)R system and inducible nitric oxide synthase (iNOS) for dual‐...

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Detalles Bibliográficos
Autores principales: Cinar, Resat, Park, Joshua K., Zawatsky, Charles N., Coffey, Nathan J., Bodine, Steven P., Abdalla, Jasmina, Yokoyama, Tadafumi, Jourdan, Tony, Jay, Lindsey, Zuo, Mei Xing G., O'Brien, Kevin J., Huang, Junfeng, Mackie, Ken, Alimardanov, Asaf, Iyer, Malliga R., Gahl, William A., Kunos, George, Gochuico, Bernadette R., Malicdan, May Christine V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255071/
https://www.ncbi.nlm.nih.gov/pubmed/34323400
http://dx.doi.org/10.1002/ctm2.471