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Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives

Helicobacter pylori causes chronic gastritis through cag pathogenicity island (cagPAI), vacuolating cytotoxin A (VacA), lipopolysaccharides (LPS), and flagellin as pathogen-related molecular patterns (PAMPs), which, in combination with the pattern recognition receptors (PRRs) of host cells promotes...

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Detalles Bibliográficos
Autores principales: Choi, Hye Ri, Lim, Hyun, Lee, Ju Hee, Park, Haeil, Kim, Hyun Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255143/
https://www.ncbi.nlm.nih.gov/pubmed/33653970
http://dx.doi.org/10.4062/biomolther.2020.192