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System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2

The worldwide circulation of different viruses coupled with the increased frequency and diversity of new outbreaks, strongly highlight the need for new antiviral drugs to quickly react against potential pandemic pathogens. Broad-spectrum antiviral agents (BSAAs) represent the ideal option for a prom...

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Detalles Bibliográficos
Autores principales: Vicenti, Ilaria, Martina, Maria Grazia, Boccuto, Adele, De Angelis, Marta, Giavarini, Giorgia, Dragoni, Filippo, Marchi, Serena, Trombetta, Claudia Maria, Crespan, Emmanuele, Maga, Giovanni, Eydoux, Cecilia, Decroly, Etienne, Montomoli, Emanuele, Nencioni, Lucia, Zazzi, Maurizio, Radi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255191/
https://www.ncbi.nlm.nih.gov/pubmed/34273661
http://dx.doi.org/10.1016/j.ejmech.2021.113683