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Kinectin 1 promotes the growth of triple-negative breast cancer via directly co-activating NF-kappaB/p65 and enhancing its transcriptional activity

Triple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer. Various endeavor has been made to explore the molecular biology basis of TNBC. Herein, we reported a novel function of factor Kinectin 1 (KTN1) as a carcinogenic promoter in TNBC. KTN1 expression in TNBC was incre...

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Detalles Bibliográficos
Autores principales: Gao, Lin, Chen, Shanze, Hong, Malin, Zhou, Wenbin, Wang, Bilan, Qiu, Junying, Xia, Jinquan, Zhao, Pan, Fu, Li, Wang, Jigang, Dai, Yong, Xie, Ni, Yang, Qinhe, Huang, Hsien-Da, Gao, Xiang, Zou, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255318/
https://www.ncbi.nlm.nih.gov/pubmed/34219129
http://dx.doi.org/10.1038/s41392-021-00652-x