Pathological Neuroinflammatory Conversion of Reactive Astrocytes Is Induced by Microglia and Involves Chromatin Remodeling

Following brain injury or in neurodegenerative diseases, astrocytes become reactive and may suffer pathological remodeling, features of which are the loss of their homeostatic functions and a pro-inflammatory gain of function that facilitates neurodegeneration. Pharmacological intervention to modula...

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Detalles Bibliográficos
Autores principales: Villarreal, Alejandro, Vidos, Camila, Monteverde Busso, Matías, Cieri, María Belén, Ramos, Alberto Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255379/
https://www.ncbi.nlm.nih.gov/pubmed/34234677
http://dx.doi.org/10.3389/fphar.2021.689346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255379/
https://www.ncbi.nlm.nih.gov/pubmed/34234677
http://dx.doi.org/10.3389/fphar.2021.689346

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