Restoration of Cavernous Veno-Occlusive Function through Chronic Administration of a Jun-Amino Terminal Kinase Inhibitor and a LIM-Kinase 2 Inhibitor by Suppressing Cavernous Apoptosis and Fibrosis in a Rat Model of Cavernous Nerve Injury: A Comparison with a Phosphodiesterase Type 5 Inhibitor

PURPOSE: To determine if chronic administration of Jun-amino terminal kinase (JNK)-inhibitors and LIM-kinase 2 (LIMK2)-inhibitors from the immediate post-injury period in a rat model of cavernous-nerve-crush-injury could normalize cavernous-veno-occlusive-function, and to compare it with phosphodies...

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Detalles Bibliográficos
Autores principales: Cho, Min Chul, Lee, Junghoon, Park, Juhyun, Kim, Soo Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255392/
https://www.ncbi.nlm.nih.gov/pubmed/32777863
http://dx.doi.org/10.5534/wjmh.200085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255392/
https://www.ncbi.nlm.nih.gov/pubmed/32777863
http://dx.doi.org/10.5534/wjmh.200085

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