OTEH-9. scRNA sequencing of proneural GBM avatar model reveals acquisition of oncogenic transcriptional programming and infers a developmental path towards a genomically unstable state

Glioblastomas (GBMs) are the most common malignant primary brain tumors, and the paucity of novel treatments warrants an investigation of its origins and development into aggressive, lethal tumors. Koga & Chaim et al. have recently shown that human pluripotent stem cells (hiPSCs) with different...

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Detalles Bibliográficos
Autores principales: Taylor, Brett M, Chaim, Isaac A, Koga, Tomoyuki, Miki, Shunichiro, Yee, Brian E, Yeo, Gene W, Furnari, Frank B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255420/
http://dx.doi.org/10.1093/noajnl/vdab070.048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255420/
http://dx.doi.org/10.1093/noajnl/vdab070.048

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