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OTME-18. Targeted CRISPR/Cas9 gene-editing regulates the brain tumor environment

Glioblastoma multiform (GBM) is the most common malignant brain tumor. Recent immunotherapy has demonstrated potential to treat GBM. However, the immune suppressive tumor environment in the brain represents a significant barrier for the treatment of GBM. Overexpression of programmed death ligand-1 (...

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Detalles Bibliográficos
Autores principales: Perez, Joshua, Fierro, Javier, Aguilar, Rocio, Dou, Huanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255424/
http://dx.doi.org/10.1093/noajnl/vdab070.069