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ECOA-6. Genomic and transcriptomic analyses reveal diverse mechanisms responsible for deregulation of epigenetic enzyme/modifier expression in glioblastoma

Malignant gliomas represent over 70% of primary brain tumors and the most deadly is glioblastoma (GBM, WHO grade IV), due to frequent dysfunctions of tumor suppressors or/and oncogenes. Recent whole genome studies of gliomas demonstrated that besides genetic alterations, epigenetic dysfunctions cont...

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Detalles Bibliográficos
Autores principales: Maleszewska, Marta, Wojtas, Bartosz, Gielniewski, Bartlomiej, Mondal, Shamba, Mieczkowski, Jakub, Dabrowski, Michal, Siedlecki, Janusz, Bujko, Mateusz, Naumann, Pawel, Grajkowska, Wieslawa, Kotulska, Katarzyna, Kaminska, Bozena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255426/
http://dx.doi.org/10.1093/noajnl/vdab070.006