OMRT-5. Therapy-induced reprogramming drives glioma vascular transdifferentiation and recurrence

Therapy-resistant glioma cells elicit remarkable phenotypic plasticity leading to aggressive tumor recurrence. Here, we used single-cell and whole transcriptomic sequencing to uncover that radiation treatment induces a dynamic shift in functional states of glioma cells allowing for acquisition of ei...

Descripción completa

Detalles Bibliográficos
Autores principales: Muthukrishnan, Sree Deepthi, Kawaguchi, Riki, Nair, Pooja, Prasad, Rachna, Qin, Yue, Condro, Michael, Wang, Qing, Alvarado, Alvaro, Kornblum, Harley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255432/
http://dx.doi.org/10.1093/noajnl/vdab070.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255432/
http://dx.doi.org/10.1093/noajnl/vdab070.030

Ejemplares similares