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NGMA-3. Use of multi-omics data to initialize and validate a causal model of glioblastoma stem cell signaling

Glioblastomas and glioblastoma stem cells are heterogeneous with respect to mutations, gene expression, and response to drugs. To make predictive responses of individual GBM stem cell lines to drugs, we have constructed a causal model of glioblastoma stem cell signaling. The core model was built sta...

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Detalles Bibliográficos
Autores principales: Holtzapple, Emilee, Miskov-Zivanov, Natasa, Cochran, Brent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255434/
http://dx.doi.org/10.1093/noajnl/vdab070.018