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OPTC-5. Molecular signatures of podoplanin expressing glioblastoma cell subsets with putative role in cancer associated thrombosis and microthrombosis

Vascular anomalies, including thrombosis, are a hallmark of glioblastoma (GBM) and an aftermath of dysregulated cancer cell genome and epigenome. Upregulation of podoplanin (PDPN) by cancer cells has recently been linked to an increased risk of venous thromboembolism in glioblastoma patients. Thus,...

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Detalles Bibliográficos
Autores principales: Tawil, Nadim, Bassawon, Rayhaan, Meehan, Brian, Montermini, Laura, Choi, Dongsic, Nehme, Ali, Najafabadi, Hamed, Riazalhosseini, Yasser, De Jay, Nicolas, Kleinman, Claudia, Gayden, Tenzin, Spinelli, Cristiana, Adnani, Lata, Couturier, Charles, Petrecca, Kevin, Jabado, Nada, Rak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255448/
http://dx.doi.org/10.1093/noajnl/vdab070.026