NGMA-2. Dual sgRNA-directed PD-L1 knockout in human glioblastoma cells using the CRISPR/Cas9 system

Glioblastoma multiforme (GBM) is an astrocyte derived brain tumor. It induces an immunosuppressive microenvironment by exploiting immune checkpoints such as the PD-1/PD-L1 pathway. Targeting the PD-1/PD-L1 pathway for immunotherapy is a promising new avenue for treating GBM, but more work is needed...

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Detalles Bibliográficos
Autores principales: Fierro, Javier, Dipasquale, Jake, Aguilar, Rocio, Perez, Joshua, Tran, An, Factoriza, Chris, Dou, Huanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255453/
http://dx.doi.org/10.1093/noajnl/vdab070.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255453/
http://dx.doi.org/10.1093/noajnl/vdab070.017

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